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5′-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by (19)F NMR
The high sensitivity of (19)F nucleus to changes in the chemical environment has promoted the use of fluorine-labeled molecular probes to study structure and interactions of nucleic acids by (19)F NMR. So far, most efforts have focused on incorporating the fluorine atom into nucleobase and ribose mo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470941/ https://www.ncbi.nlm.nih.gov/pubmed/32514551 http://dx.doi.org/10.1093/nar/gkaa470 |