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5′-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by (19)F NMR

The high sensitivity of (19)F nucleus to changes in the chemical environment has promoted the use of fluorine-labeled molecular probes to study structure and interactions of nucleic acids by (19)F NMR. So far, most efforts have focused on incorporating the fluorine atom into nucleobase and ribose mo...

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Detalles Bibliográficos
Autores principales: Baranowski, Marek R, Warminski, Marcin, Jemielity, Jacek, Kowalska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470941/
https://www.ncbi.nlm.nih.gov/pubmed/32514551
http://dx.doi.org/10.1093/nar/gkaa470