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Flow cytometry assay for the detection of single-copy DNA in human lymphocytes
Specific nucleic acid sequences can be detected in individual cells by in situ hybridization. However, when very few copies of a target sequence are present per cell, its signal is undetectable by flow cytometry. Although various approaches have been developed to increase fluorescence signals for in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470942/ https://www.ncbi.nlm.nih.gov/pubmed/32544240 http://dx.doi.org/10.1093/nar/gkaa515 |