Landscape of DNA binding signatures of myocyte enhancer factor-2B reveals a unique interplay of base and shape readout

Myocyte enhancer factor-2B (MEF2B) has the unique capability of binding to its DNA target sites with a degenerate motif, while still functioning as a gene-specific transcriptional regulator. Identifying its DNA targets is crucial given regulatory roles exerted by members of the MEF2 family and MEF2B...

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Detalles Bibliográficos
Autores principales: Dantas Machado, Ana Carolina, Cooper, Brendon H, Lei, Xiao, Di Felice, Rosa, Chen, Lin, Rohs, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470950/
https://www.ncbi.nlm.nih.gov/pubmed/32738045
http://dx.doi.org/10.1093/nar/gkaa642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470950/
https://www.ncbi.nlm.nih.gov/pubmed/32738045
http://dx.doi.org/10.1093/nar/gkaa642

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