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Landscape of DNA binding signatures of myocyte enhancer factor-2B reveals a unique interplay of base and shape readout
Myocyte enhancer factor-2B (MEF2B) has the unique capability of binding to its DNA target sites with a degenerate motif, while still functioning as a gene-specific transcriptional regulator. Identifying its DNA targets is crucial given regulatory roles exerted by members of the MEF2 family and MEF2B...
Autores principales: | Dantas Machado, Ana Carolina, Cooper, Brendon H, Lei, Xiao, Di Felice, Rosa, Chen, Lin, Rohs, Remo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470950/ https://www.ncbi.nlm.nih.gov/pubmed/32738045 http://dx.doi.org/10.1093/nar/gkaa642 |
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