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Dnmt1 binds and represses genomic retroelements via DNA methylation in mouse early embryos
Genome-wide passive DNA demethylation in cleavage-stage mouse embryos is related to the cytoplasmic localization of the maintenance methyltransferase DNMT1. However, recent studies provided evidences of the nuclear localization of DNMT1 and its contribution to the maintenance of methylation levels o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470951/ https://www.ncbi.nlm.nih.gov/pubmed/32667642 http://dx.doi.org/10.1093/nar/gkaa584 |