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Dnmt1 binds and represses genomic retroelements via DNA methylation in mouse early embryos

Genome-wide passive DNA demethylation in cleavage-stage mouse embryos is related to the cytoplasmic localization of the maintenance methyltransferase DNMT1. However, recent studies provided evidences of the nuclear localization of DNMT1 and its contribution to the maintenance of methylation levels o...

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Detalles Bibliográficos
Autores principales: Min, Byungkuk, Park, Jung Sun, Jeong, Young Sun, Jeon, Kyuheum, Kang, Yong-Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470951/
https://www.ncbi.nlm.nih.gov/pubmed/32667642
http://dx.doi.org/10.1093/nar/gkaa584