Cargando…

High-throughput methods for measuring DNA thermodynamics

Understanding the thermodynamics of DNA motifs is important for prediction and design of probes and primers, but melt curve analyses are low-throughput and produce inaccurate results for motifs such as bulges and mismatches. Here, we developed a new, accurate and high-throughput method for measuring...

Descripción completa

Detalles Bibliográficos
Autores principales: Bae, Jin H, Fang, John Z, Zhang, David Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470960/
https://www.ncbi.nlm.nih.gov/pubmed/32544247
http://dx.doi.org/10.1093/nar/gkaa521