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Switching the activity of Taq polymerase using clamp-like triplex aptamer structure

In nature, allostery is the principal approach for regulating cellular processes and pathways. Inspired by nature, structure-switching aptamer-based nanodevices are widely used in artificial biotechnologies. However, the canonical aptamer structures in the nanodevices usually adopt a duplex form, wh...

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Detalles Bibliográficos
Autores principales: Hu, Yingxin, Wang, Zhiyu, Chen, Zhekun, Pan, Linqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470972/
https://www.ncbi.nlm.nih.gov/pubmed/32644133
http://dx.doi.org/10.1093/nar/gkaa581