Use of CRISPR-Cas9 To Target Homologous Recombination Limits Transformation-Induced Genomic Changes in Candida albicans

Most of our knowledge relating to molecular mechanisms of human fungal pathogenesis in Candida albicans relies on reverse genetics approaches, requiring strain engineering. DNA-mediated transformation of C. albicans has been described as highly mutagenic, potentially accentuated by the organism’s ge...

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Detalles Bibliográficos
Autores principales: Marton, Timea, Maufrais, Corinne, d’Enfert, Christophe, Legrand, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471004/
https://www.ncbi.nlm.nih.gov/pubmed/32878930
http://dx.doi.org/10.1128/mSphere.00620-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471004/
https://www.ncbi.nlm.nih.gov/pubmed/32878930
http://dx.doi.org/10.1128/mSphere.00620-20

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