MAb NJ001 inhibits lung adenocarcinoma invasiveness by directly regulating TIMP‐3 promoter activity via FOXP1 binding sites

BACKGROUND: Previously, we developed a monoclonal antibody (mAb) NJ001 that binds to the antigen SP70 in human non‐small cell lung cancer (NSCLC) cells and showed it could inhibit lung adenocarcinoma (AD) growth. Here, we investigated the effect and mechanisms of NJ001 in lung AD metastasis. METHODS...

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Detalles Bibliográficos
Autores principales: Gu, Chunrong, Luo, Ying, Zhang, Shichang, Xu, Jian, Zhang, Jiexin, Ju, Huanyu, Liu, Jingping, Zhang, Lixia, Zhang, Yan, Wu, Lei, Xie, Erfu, Xu, Ting, Pan, Shiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471035/
https://www.ncbi.nlm.nih.gov/pubmed/32744429
http://dx.doi.org/10.1111/1759-7714.13593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471035/
https://www.ncbi.nlm.nih.gov/pubmed/32744429
http://dx.doi.org/10.1111/1759-7714.13593

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