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Antibiotics impair immune checkpoint inhibitor effectiveness in Hispanic patients with non‐small cell lung cancer (AB‐CLICaP)

BACKGROUND: The intestinal microbiota is an important factor in modulating immune‐mediated tumor cell destruction. Alterations in the microbiome composition have been linked to reduced efficacy of immune checkpoint inhibitor (ICI) therapies. Therefore, antibiotic treatment (ATB), which modifies the...

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Detalles Bibliográficos
Autores principales: Ruiz‐Patiño, Alejandro, Barrón, Feliciano, Cardona, Andrés F., Corrales, Luis, Mas, Luis, Martín, Claudio, Zatarain‐Barrón, Zyanya L., Recondo, Gonzalo, Ricaurte, Luisa, Rojas, Leonardo, Archila, Pilar, Rodríguez, July, Sotelo, Carolina, Viola, Lucia, Vargas, Carlos, Carranza, Hernán, Otero, Jorge, Pino, Luis E., Rolfo, Christian, Rosell, Rafael, Arrieta, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471049/
https://www.ncbi.nlm.nih.gov/pubmed/32705787
http://dx.doi.org/10.1111/1759-7714.13573