In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix

Our understanding of the spatiotemporal regulation of cardiogenesis is hindered by the difficulties in modeling this complex organ currently by in vitro models. Here we develop a method to generate heart organoids from mouse embryonic stem cell-derived embryoid bodies. Consecutive morphological chan...

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Detalles Bibliográficos
Autores principales: Lee, Jiyoung, Sutani, Akito, Kaneko, Rin, Takeuchi, Jun, Sasano, Tetsuo, Kohda, Takashi, Ihara, Kensuke, Takahashi, Kentaro, Yamazoe, Masahiro, Morio, Tomohiro, Furukawa, Tetsushi, Ishino, Fumitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471119/
https://www.ncbi.nlm.nih.gov/pubmed/32883967
http://dx.doi.org/10.1038/s41467-020-18031-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471119/
https://www.ncbi.nlm.nih.gov/pubmed/32883967
http://dx.doi.org/10.1038/s41467-020-18031-5

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