Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

Suprabasin (SBSN) is expressed not only in epidermis but also in epithelial cells of the upper digestive tract where metals such as nickel are absorbed. We have recently shown that SBSN level is decreased in the stratum corneum and serum of atopic dermatitis (AD) patients, especially in intrinsic AD...

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Detalles Bibliográficos
Autores principales: Nakazawa, Shinsuke, Shimauchi, Takatoshi, Funakoshi, Atsuko, Aoshima, Masahiro, Phadungsaksawasdi, Pawit, Sakabe, Jun-ichi, Asakawa, Sanki, Hirasawa, Noriyasu, Ito, Taisuke, Tokura, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471289/
https://www.ncbi.nlm.nih.gov/pubmed/32884021
http://dx.doi.org/10.1038/s41598-020-71536-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471289/
https://www.ncbi.nlm.nih.gov/pubmed/32884021
http://dx.doi.org/10.1038/s41598-020-71536-3

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