Aggravated ulcerative colitis caused by intestinal Metrnl deficiency is associated with reduced autophagy in epithelial cells

Metrnl is a newly identified secreted protein highly expressed in the intestinal epithelium. This study aimed to explore the role and mechanism of intestinal epithelial Metrnl in ulcerative colitis. Metrnl(−/−) (intestinal epithelial cell-specific Metrnl knockout) mice did not display any phenotypes...

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Detalles Bibliográficos
Autores principales: Zhang, Sai-long, Li, Zhi-yong, Wang, Dong-sheng, Xu, Tian-ying, Fan, Mao-bing, Cheng, Ming-he, Miao, Chao-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471395/
https://www.ncbi.nlm.nih.gov/pubmed/31949292
http://dx.doi.org/10.1038/s41401-019-0343-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471395/
https://www.ncbi.nlm.nih.gov/pubmed/31949292
http://dx.doi.org/10.1038/s41401-019-0343-4

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