DL0410 ameliorates cognitive deficits in APP/PS1 transgenic mice by promoting synaptic transmission and reducing neuronal loss

At present, few available drugs can be used to either improve pathological features or prevent the progression of Alzheimer’s disease (AD). DL0410 ((1,1′-([1,1′-biphenyl]-4,4′-diyl) bis (3-(piperidin-1-yl) propan-1-one) dihydrochloride) is a multiple-target small molecule that has been found to reve...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Lian, Wen-wen, Yan, Rong, Jia, Hao, Xu, Lv-jie, Wang, Lin, Liu, Ai-lin, Du, Guan-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471418/
https://www.ncbi.nlm.nih.gov/pubmed/31685977
http://dx.doi.org/10.1038/s41401-019-0312-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471418/
https://www.ncbi.nlm.nih.gov/pubmed/31685977
http://dx.doi.org/10.1038/s41401-019-0312-y

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