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The Selective Peroxisome Proliferator‐Activated Receptor Gamma Modulator CHS‐131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis

CHS‐131 is a selective peroxisome proliferator‐activated receptor gamma modulator with antidiabetic effects and less fluid retention and weight gain compared to thiazolidinediones in phase II clinical trials. We investigated the effects of CHS‐131 on metabolic parameters and liver histopathology in...

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Detalles Bibliográficos
Autores principales: Perakakis, Nikolaos, Joshi, Aditya, Peradze, Natia, Stefanakis, Konstantinos, Li, Georgia, Feigh, Michael, Veidal, Sanne Skovgard, Rosen, Glenn, Fleming, Michael, Mantzoros, Christos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471426/
https://www.ncbi.nlm.nih.gov/pubmed/32923834
http://dx.doi.org/10.1002/hep4.1558