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Targeted Inhibition of Purine Metabolism Is Effective in Suppressing Hepatocellular Carcinoma Progression

Tumor‐specific metabolic rewiring, acquired to confer a proliferative and survival advantage over nontransformed cells, represents a renewed focus in cancer therapy development. Hepatocellular carcinoma (HCC), a malignancy that has hitherto been resistant to compounds targeting oncogenic signaling p...

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Detalles Bibliográficos
Autores principales: Chong, Yong Chun, Toh, Tan Boon, Chan, Zhiling, Lin, Quy Xiao Xuan, Thng, Dexter Kai Hao, Hooi, Lissa, Ding, Zhaobing, Shuen, Timothy, Toh, Han Chong, Dan, Yock Young, Bonney, Glenn Kunnath, Zhou, Lei, Chow, Pierce, Wang, Yulan, Benoukraf, Touati, Chow, Edward Kai‐Hua, Han, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471427/
https://www.ncbi.nlm.nih.gov/pubmed/32923839
http://dx.doi.org/10.1002/hep4.1559