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Self‐Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene

Establishment of a physiologically relevant human hepatocyte‐like cell system for in vitro translational research has been hampered by the limited availability of cell models that accurately reflect human biology and the pathophysiology of human disease. Here we report a robust, reproducible, and sc...

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Detalles Bibliográficos
Autores principales: Abbey, Deepti, Elwyn, Susannah, Hand, Nicholas J., Musunuru, Kiran, Rader, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471428/
https://www.ncbi.nlm.nih.gov/pubmed/32923835
http://dx.doi.org/10.1002/hep4.1538