Cargando…
Self‐Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene
Establishment of a physiologically relevant human hepatocyte‐like cell system for in vitro translational research has been hampered by the limited availability of cell models that accurately reflect human biology and the pathophysiology of human disease. Here we report a robust, reproducible, and sc...
Autores principales: | Abbey, Deepti, Elwyn, Susannah, Hand, Nicholas J., Musunuru, Kiran, Rader, Daniel J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471428/ https://www.ncbi.nlm.nih.gov/pubmed/32923835 http://dx.doi.org/10.1002/hep4.1538 |
Ejemplares similares
-
Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism
por: Abbey, Deepti, et al.
Publicado: (2021) -
Regulation of TRIB1 abundance in hepatocyte models in response to proteasome inhibition
por: Soubeyrand, Sébastien, et al.
Publicado: (2023) -
TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha
por: Soubeyrand, Sébastien, et al.
Publicado: (2017) -
Trib2 regulates the pluripotency of embryonic stem cells and enhances reprogramming efficiency
por: Do, Eun Kyoung, et al.
Publicado: (2017) -
Genome editing of human pluripotent stem cells to generate human cellular disease models
por: Musunuru, Kiran
Publicado: (2013)