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TLR4 deficiency has a protective effect in the MPTP/probenecid mouse model of Parkinson’s disease
Parkinson’s disease (PD) is a multifactorial disorder characterized by progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) and the presence of Lewy bodies (LBs) consisting of misfolded α-synuclein protein. The etiology of PD is still not clear but systemic infl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471440/ https://www.ncbi.nlm.nih.gov/pubmed/31388087 http://dx.doi.org/10.1038/s41401-019-0280-2 |