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Evaluation of a novel monoclonal antibody mAb109 by immuno-PET/fluorescent imaging for noninvasive lung adenocarcinoma diagnosis
Monoclonal antibodies are believed to be magic bullets and hold great potential for lots of biological process. About 100 μg of mAb109 was expressed in 5 × 10(6) cells after 10 days’ immunization. (64)Cu-NOTA-mAb109 was synthesized with the specific activity of 0.74 MBq/μg and high in vitro stabilit...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471445/ https://www.ncbi.nlm.nih.gov/pubmed/31534200 http://dx.doi.org/10.1038/s41401-019-0294-9 |