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Evaluation of a novel monoclonal antibody mAb109 by immuno-PET/fluorescent imaging for noninvasive lung adenocarcinoma diagnosis

Monoclonal antibodies are believed to be magic bullets and hold great potential for lots of biological process. About 100 μg of mAb109 was expressed in 5 × 10(6) cells after 10 days’ immunization. (64)Cu-NOTA-mAb109 was synthesized with the specific activity of 0.74 MBq/μg and high in vitro stabilit...

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Detalles Bibliográficos
Autores principales: Zhu, Hua, Liu, Te-li, Liu, Chang-hao, Wang, Jing, Zhang, Hong, Dong, Bin, Shen, Jing, Zhao, Chuan-ke, Li, Zhen-fu, Cheng, Zhen, Yang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471445/
https://www.ncbi.nlm.nih.gov/pubmed/31534200
http://dx.doi.org/10.1038/s41401-019-0294-9