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23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9

23,24-Dihydrocucurbitacin B (designated as C95 in this article) is a cucurbitane triterpenoid that has been shown to possess a variety of pharmacological activities, such as anti-inflammatory and anti-HIV-1 activities etc. In this study, we investigated the effects of 23,24-dihydrocucurbitacin B on...

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Detalles Bibliográficos
Autores principales: Li, Hui-hui, Li, Jun, Zhang, Xian-jing, Li, Jiao-meng, Xi, Cong, Wang, Wen-qiong, Lu, You-li, Xuan, Li-jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471448/
https://www.ncbi.nlm.nih.gov/pubmed/31358898
http://dx.doi.org/10.1038/s41401-019-0274-0