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RepSox, a small molecule inhibitor of the TGFβ receptor, induces brown adipogenesis and browning of white adipocytes

Unlike white adipose tissue (WAT), brown adipose tissue (BAT) is mainly responsible for energy expenditure via thermogenesis by uncoupling the respiratory chain. Promoting the differentiation of brown fat precursor cells and the browning of white fat have become a research hotspot for the treatment...

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Detalles Bibliográficos
Autores principales: Tu, Wan-zhi, Fu, Yan-bin, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471457/
https://www.ncbi.nlm.nih.gov/pubmed/31235818
http://dx.doi.org/10.1038/s41401-019-0264-2