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Huperzine A ameliorates obesity-related cognitive performance impairments involving neuronal insulin signaling pathway in mice

Type 2 diabetes (T2D) and Alzheimer’s disease (AD) share several common pathophysiological features. Huperzine A (Hup A), a Lycopodium alkaloid extracted from the Chinese herb moss Huperzia serrata, is a specific and reversible inhibitor of acetylcholinesterase, which is clinically used for the trea...

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Detalles Bibliográficos
Autores principales: Wang, Hong-ying, Wu, Min, Diao, Jun-ling, Li, Ji-bin, Sun, Yu-xiang, Xiao, Xiao-qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471460/
https://www.ncbi.nlm.nih.gov/pubmed/31213670
http://dx.doi.org/10.1038/s41401-019-0257-1