Nimesulide increases the aldehyde oxidase activity of humans and rats

An increasing number of drugs are metabolized by aldehyde oxidase (AOX), but AOX-mediated drug interactions are seldom reported due to the lack of appropriate inhibitors and inducers. A recent study reported that nimesulide (NIM) could increase the liver injury risk of methotrexate. The latter was m...

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Detalles Bibliográficos
Autores principales: Zhou, Lei, Pang, Xiao-yan, Hou, Xiang-yu, Liu, Lu, Guo, Zi-tao, Chen, Xiao-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471466/
https://www.ncbi.nlm.nih.gov/pubmed/31913347
http://dx.doi.org/10.1038/s41401-019-0336-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471466/
https://www.ncbi.nlm.nih.gov/pubmed/31913347
http://dx.doi.org/10.1038/s41401-019-0336-3

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