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Nimesulide increases the aldehyde oxidase activity of humans and rats
An increasing number of drugs are metabolized by aldehyde oxidase (AOX), but AOX-mediated drug interactions are seldom reported due to the lack of appropriate inhibitors and inducers. A recent study reported that nimesulide (NIM) could increase the liver injury risk of methotrexate. The latter was m...
Autores principales: | Zhou, Lei, Pang, Xiao-yan, Hou, Xiang-yu, Liu, Lu, Guo, Zi-tao, Chen, Xiao-yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471466/ https://www.ncbi.nlm.nih.gov/pubmed/31913347 http://dx.doi.org/10.1038/s41401-019-0336-3 |
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