PK/PD modeling based on NO-ET homeostasis for improving management of sunitinib-induced hypertension in rats

Sunitinib is an oral small molecule multitargeted tyrosine kinase inhibitor, which is currently used to treat severe cancers. Clinical research has shown that patients treated with sunitinib develop hypertension. As soon as sunitinib-induced hypertension appears, it is usual to administer anti-hyper...

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Detalles Bibliográficos
Autores principales: Liu, Hao-chen, Zhou, Xiao-ting, Zheng, Yun-si, He, Hua, Liu, Xiao-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471499/
https://www.ncbi.nlm.nih.gov/pubmed/31932646
http://dx.doi.org/10.1038/s41401-019-0331-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471499/
https://www.ncbi.nlm.nih.gov/pubmed/31932646
http://dx.doi.org/10.1038/s41401-019-0331-8

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