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Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation

The transcription factor zinc finger E-box binding protein 2 (ZEB2) controls embryonic and adult cell fate decisions and cellular maturation in many stem/progenitor cell types. Defects in these processes in specific cell types underlie several aspects of Mowat–Wilson syndrome (MOWS), which is caused...

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Detalles Bibliográficos
Autores principales: Birkhoff, Judith C, Brouwer, Rutger W W, Kolovos, Petros, Korporaal, Anne L, Bermejo-Santos, Ana, Boltsis, Ilias, Nowosad, Karol, van den Hout, Mirjam C G N, Grosveld, Frank G, van IJcken, Wilfred F J, Huylebroeck, Danny, Conidi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471508/
https://www.ncbi.nlm.nih.gov/pubmed/32628253
http://dx.doi.org/10.1093/hmg/ddaa141