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Pharmacokinetics and Monte Carlo Dosing Simulations of Imipenem in Critically Ill Patients with Life-Threatening Severe Infections During Support with Extracorporeal Membrane Oxygenation

BACKGROUND: Extracorporeal membrane oxygenation (ECMO), a cardiopulmonary bypass device, has been found to increase the profound pathophysiological changes associated with life-threatening severe infections in patients with multiple comorbidities, which results in alterations of pharmacokinetic patt...

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Detalles Bibliográficos
Autores principales: Jaruratanasirikul, Sutep, Vattanavanit, Veerapong, Wongpoowarak, Wibul, Nawakitrangsan, Monchana, Samaeng, Maseetoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471576/
https://www.ncbi.nlm.nih.gov/pubmed/32886347
http://dx.doi.org/10.1007/s13318-020-00643-3