Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy

Glioblastoma (GBM) metabolism has traditionally been characterized by a primary dependence on aerobic glycolysis, prompting the use of the ketogenic diet (KD) as a potential therapy. In this study we evaluated the effectiveness of the KD in GBM and assessed the role of fatty acid oxidation (FAO) in...

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Detalles Bibliográficos
Autores principales: Sperry, Jantzen, Condro, Michael C., Guo, Lea, Braas, Daniel, Vanderveer-Harris, Nathan, Kim, Kristen K.O., Pope, Whitney B., Divakaruni, Ajit S., Lai, Albert, Christofk, Heather, Castro, Maria G., Lowenstein, Pedro R., Le Belle, Janel E., Kornblum, Harley I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471621/
https://www.ncbi.nlm.nih.gov/pubmed/32861192
http://dx.doi.org/10.1016/j.isci.2020.101453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471621/
https://www.ncbi.nlm.nih.gov/pubmed/32861192
http://dx.doi.org/10.1016/j.isci.2020.101453

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