p53 Affects PGC1α Stability Through AKT/GSK-3β to Enhance Cisplatin Sensitivity in Non-Small Cell Lung Cancer

Drug resistance greatly limits the therapeutic efficacy of treatment of non-small cell lung cancer (NSCLC). One of the important factors is the dysfunction of tumor suppressor p53. Recent studies have suggested that p53 suppresses tumors by regulating number of mitochondrial proteins, including pero...

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Detalles Bibliográficos
Autores principales: Deng, Xinyue, Li, Yang, Gu, Shuang, Chen, Yingying, Yu, Bingbing, Su, Jing, Sun, Liankun, Liu, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471661/
https://www.ncbi.nlm.nih.gov/pubmed/32974127
http://dx.doi.org/10.3389/fonc.2020.01252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471661/
https://www.ncbi.nlm.nih.gov/pubmed/32974127
http://dx.doi.org/10.3389/fonc.2020.01252

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