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p53 Affects PGC1α Stability Through AKT/GSK-3β to Enhance Cisplatin Sensitivity in Non-Small Cell Lung Cancer
Drug resistance greatly limits the therapeutic efficacy of treatment of non-small cell lung cancer (NSCLC). One of the important factors is the dysfunction of tumor suppressor p53. Recent studies have suggested that p53 suppresses tumors by regulating number of mitochondrial proteins, including pero...
Autores principales: | Deng, Xinyue, Li, Yang, Gu, Shuang, Chen, Yingying, Yu, Bingbing, Su, Jing, Sun, Liankun, Liu, Yanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471661/ https://www.ncbi.nlm.nih.gov/pubmed/32974127 http://dx.doi.org/10.3389/fonc.2020.01252 |
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