The MeCP2E1/E2-BDNF-miR132 Homeostasis Regulatory Network Is Region-Dependent in the Human Brain and Is Impaired in Rett Syndrome Patients

Rett Syndrome (RTT) is a rare and progressive neurodevelopmental disorder that is caused by de novo mutations in the X-linked Methyl CpG binding protein 2 (MECP2) gene and is subjected to X-chromosome inactivation. RTT is commonly associated with neurological regression, autistic features, motor con...

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Detalles Bibliográficos
Autores principales: Pejhan, Shervin, Del Bigio, Marc R., Rastegar, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471663/
https://www.ncbi.nlm.nih.gov/pubmed/32974336
http://dx.doi.org/10.3389/fcell.2020.00763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471663/
https://www.ncbi.nlm.nih.gov/pubmed/32974336
http://dx.doi.org/10.3389/fcell.2020.00763

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