Pro-apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro

In order to develop potential anticancer agents stimulating apoptosis, novel 3,4-isoxazolediamide and 4,5,6,7-tetrahydro-isoxazolo-[4,5-c]-pyridine derivatives have been synthetized. The original structures of geldanamycin and radicicol, which are known natural heat shock protein (HSP) inhibitors, w...

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Detalles Bibliográficos
Autores principales: Lampronti, Ilaria, Simoni, Daniele, Rondanin, Riccardo, Baruchello, Riccardo, Scapoli, Chiara, Finotti, Alessia, Borgatti, Monica, Tupini, Chiara, Gambari, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471682/
https://www.ncbi.nlm.nih.gov/pubmed/32934719
http://dx.doi.org/10.3892/ol.2020.12002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471682/
https://www.ncbi.nlm.nih.gov/pubmed/32934719
http://dx.doi.org/10.3892/ol.2020.12002

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