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Association between MDR1 polymorphisms and XELIRI and XELOX chemoresistance in Saudi patients with colorectal cancer

Multidrug resistance member 1 (MDR1) is located on chromosome 7 and encodes P-glycoprotein, which is universally accepted as a drug resistance biomarker. MDR1 polymorphisms can alter protein expression or function, which has been previously reported to associate with various types of malignancies, s...

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Detalles Bibliográficos
Autores principales: Al-Ghafari, Ayat B., Al Qahtani, Areej M., Alturki, Suzan N., Al Doghaither, Huda A., Elmorsy, Ekramy M., Tashkandi, Hanaa M., Abusanad, Atlal M., Alkhayyat, Shadi S., Omar, Ulfat M., Zeeneldin, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471754/
https://www.ncbi.nlm.nih.gov/pubmed/32934723
http://dx.doi.org/10.3892/ol.2020.12016