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α-Lipoic Acid Maintains Brain Glucose Metabolism via BDNF/TrkB/HIF-1α Signaling Pathway in P301S Mice

The microtubule-associated protein tau is closely correlated with hypometabolism in Alzheimer’s disease (AD). α-lipoic acid (LA), which is a naturally occurring cofactor in mitochondrial, has been shown to have properties that can inhibit the tau pathology and neuronal damage in our previous researc...

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Detalles Bibliográficos
Autores principales: Zhang, Yan-hui, Yan, Xin-zhu, Xu, Shuang-feng, Pang, Zhong-qiu, Li, Lin-bo, Yang, Yang, Fan, Yong-gang, Wang, Zhuo, Yu, Xin, Guo, Chuang, Ao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471806/
https://www.ncbi.nlm.nih.gov/pubmed/32973490
http://dx.doi.org/10.3389/fnagi.2020.00262