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Autoantigens PLA2R and THSD7A in membranous nephropathy share a common epitope motif in the N-terminal domain
Patients with membranous nephropathy have autoantibodies against PLA2R (up to 80%), or THSD7A (up to 2%). We previously described the immunodominant epitope within PLA2R but epitopes in THSD7A are still unknown. To find anti-THSD7A sera for this study, we screened 1843 sera from biopsy-proven MN pat...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471840/ https://www.ncbi.nlm.nih.gov/pubmed/31395435 http://dx.doi.org/10.1016/j.jaut.2019.102308 |