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Influence of n-acetylcysteine maintenance on the pharmacodynamic effects of oral ethanol

RATIONALE: Glutamate systems play an important role in the abuse related effects of alcohol. n-Acetylcysteine, a drug that promotes glutamate homeostasis, attenuates a range of alcohol effects in preclinical models. OBJECTIVES: This human laboratory study determined the influence of n-acetylcysteine...

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Detalles Bibliográficos
Autores principales: Stoops, William W., Strickland, Justin C., Hays, Lon R., Rayapati, Abner O., Lile, Joshua A., Rush, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471929/
https://www.ncbi.nlm.nih.gov/pubmed/32891709
http://dx.doi.org/10.1016/j.pbb.2020.173037