Cargando…

RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A

Regulatory factor X-5 (RFX5) represents a key transcription regulator of MHCII gene expression in the immune system. This study aims to explore the molecular mechanisms and biological significance of RFX5. Firstly, by analyzing ENCODE chromatin immunoprecipitation (ChIP)-seq in HepG2 and TCGA RNA-se...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Dong-Bo, Xie, Xing-Wang, Zhao, Yang-Jing, Wang, Xue-Yan, Liao, Wei-Jia, Chen, Pu, Deng, Kang-Jian, Fei, Ran, Qin, Wan-Ying, Wang, Jiang-Hua, Wu, Xu, Shao, Qi-Xiang, Wei, Lai, Chen, Hong-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471945/
https://www.ncbi.nlm.nih.gov/pubmed/32883983
http://dx.doi.org/10.1038/s41598-020-71403-1