Melatonin promotes Schwann cell dedifferentiation and proliferation through the Ras/Raf/ERK and MAPK pathways, and glial cell-derived neurotrophic factor expression

Upon peripheral nerve injury (PNI), continuous proliferation of Schwann cells is critical for axon regeneration and tubular reconstruction for nerve regeneration. Melatonin is a hormone that is able to induce proliferation in various cell types. In the present study, the effects of melatonin on prom...

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Detalles Bibliográficos
Autores principales: Tiong, Yee Lian, Ng, Khuen Yen, Koh, Rhun Yian, Ponnudurai, Gnanajothy, Chye, Soi Moi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471953/
https://www.ncbi.nlm.nih.gov/pubmed/32934681
http://dx.doi.org/10.3892/etm.2020.9143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471953/
https://www.ncbi.nlm.nih.gov/pubmed/32934681
http://dx.doi.org/10.3892/etm.2020.9143

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