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A novel monoclonal antibody against human B7-1 protects against chronic graft-vs.-host disease in a murine lupus nephritis model

Lupus nephritis (LN) is the most common complication that causes mortality in patients with systemic lupus erythematosus. The B7-1/B7-2 and CD28/cytotoxic T-lymphocyte associated protein 4 co-stimulatory pathway serves a key role in autoimmune disease and organ transplantation. The aim of the presen...

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Detalles Bibliográficos
Autores principales: Shen, Lijun, Zhu, Ying, Han, Lianhua, Wang, Yuyu, Yan, Tianming, Kong, Yong, Zou, Shitao, Qiu, Yuhua, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471967/
https://www.ncbi.nlm.nih.gov/pubmed/32934679
http://dx.doi.org/10.3892/etm.2020.9146