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α-Conotoxin Peptidomimetics: Probing the Minimal Binding Motif for Effective Analgesia
Several analgesic α-conotoxins have been isolated from marine cone snails. Structural modification of native peptides has provided potent and selective analogues for two of its known biological targets—nicotinic acetylcholine and γ-aminobutyric acid (GABA) G protein-coupled (GABA(B)) receptors. Both...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472027/ https://www.ncbi.nlm.nih.gov/pubmed/32781580 http://dx.doi.org/10.3390/toxins12080505 |