Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro

Mammarenaviruses cause chronic infections in rodents, which are their predominant natural hosts. Human infection with some of these viruses causes high-consequence disease, posing significant issues in public health. Currently, no FDA-licensed mammarenavirus vaccines are available, and anti-mammaren...

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Detalles Bibliográficos
Autores principales: Kim, Yu-Jin, Cubitt, Beatrice, Cai, Yingyun, Kuhn, Jens H., Vitt, Daniel, Kohlhof, Hella, de la Torre, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472048/
https://www.ncbi.nlm.nih.gov/pubmed/32751087
http://dx.doi.org/10.3390/v12080821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472048/
https://www.ncbi.nlm.nih.gov/pubmed/32751087
http://dx.doi.org/10.3390/v12080821

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