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Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro
Mammarenaviruses cause chronic infections in rodents, which are their predominant natural hosts. Human infection with some of these viruses causes high-consequence disease, posing significant issues in public health. Currently, no FDA-licensed mammarenavirus vaccines are available, and anti-mammaren...
Autores principales: | Kim, Yu-Jin, Cubitt, Beatrice, Cai, Yingyun, Kuhn, Jens H., Vitt, Daniel, Kohlhof, Hella, de la Torre, Juan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472048/ https://www.ncbi.nlm.nih.gov/pubmed/32751087 http://dx.doi.org/10.3390/v12080821 |
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