Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors

HIV-1 infects 39.5 million people worldwide, and cART is effective in preventing viral spread by reducing HIV-1 plasma viral loads to undetectable levels. However, viral reservoirs persist by mechanisms, including the inhibition of autophagy by HIV-1 proteins (i.e., Nef and Tat). HIV-1 reservoirs ca...

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Detalles Bibliográficos
Autores principales: Pinto, Daniel O., DeMarino, Catherine, Vo, Thy T., Cowen, Maria, Kim, Yuriy, Pleet, Michelle L., Barclay, Robert A., Noren Hooten, Nicole, Evans, Michele K., Heredia, Alonso, Batrakova, Elena V., Iordanskiy, Sergey, Kashanchi, Fatah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472203/
https://www.ncbi.nlm.nih.gov/pubmed/32823598
http://dx.doi.org/10.3390/v12080885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472203/
https://www.ncbi.nlm.nih.gov/pubmed/32823598
http://dx.doi.org/10.3390/v12080885

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