Cargando…
Low-Level Ionizing Radiation Induces Selective Killing of HIV-1-Infected Cells with Reversal of Cytokine Induction Using mTOR Inhibitors
HIV-1 infects 39.5 million people worldwide, and cART is effective in preventing viral spread by reducing HIV-1 plasma viral loads to undetectable levels. However, viral reservoirs persist by mechanisms, including the inhibition of autophagy by HIV-1 proteins (i.e., Nef and Tat). HIV-1 reservoirs ca...
Autores principales: | Pinto, Daniel O., DeMarino, Catherine, Vo, Thy T., Cowen, Maria, Kim, Yuriy, Pleet, Michelle L., Barclay, Robert A., Noren Hooten, Nicole, Evans, Michele K., Heredia, Alonso, Batrakova, Elena V., Iordanskiy, Sergey, Kashanchi, Fatah |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472203/ https://www.ncbi.nlm.nih.gov/pubmed/32823598 http://dx.doi.org/10.3390/v12080885 |
Ejemplares similares
-
Extracellular Vesicle Activation of Latent HIV-1 Is Driven by EV-Associated c-Src and Cellular SRC-1 via the PI3K/AKT/mTOR Pathway
por: Barclay, Robert A., et al.
Publicado: (2020) -
Identification of Modulators of HIV-1 Proviral Transcription from a Library of FDA-Approved Pharmaceuticals
por: Sampey, Gavin C., et al.
Publicado: (2020) -
Effect of transcription inhibition and generation of suppressive viral non-coding RNAs
por: Pinto, Daniel O., et al.
Publicado: (2019) -
Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction
por: Pleet, Michelle L., et al.
Publicado: (2016) -
Corrigendum: Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction
por: Pleet, Michelle L., et al.
Publicado: (2018)