Tick-Borne Encephalitis Virus Adaptation in Different Host Environments and Existence of Quasispecies

A highly virulent strain (Hypr) of tick-borne encephalitis virus (TBEV) was serially subcultured in the mammalian porcine kidney stable (PS) and Ixodes ricinus tick (IRE/CTVM19) cell lines, producing three viral variants. These variants exhibited distinct plaque sizes and virulence in a mouse model....

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Detalles Bibliográficos
Autores principales: Helmová, Renata, Hönig, Václav, Tykalová, Hana, Palus, Martin, Bell-Sakyi, Lesley, Grubhoffer, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472235/
https://www.ncbi.nlm.nih.gov/pubmed/32824843
http://dx.doi.org/10.3390/v12080902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472235/
https://www.ncbi.nlm.nih.gov/pubmed/32824843
http://dx.doi.org/10.3390/v12080902

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