Biomarker evidence for distal tubular damage but cortical sparing in hospitalized diabetic patients with acute kidney injury (AKI) while on SGLT2 inhibitors

BACKGROUND: Inhibitors of sodium-glucose co-transporter-2 (SGLT2i) were found to improve renal outcome in diabetic patients in large prospective randomized trials. Yet, SGLT2i may acutely reduce kidney function through volume depletion, altered glomerular hemodynamics or intensified medullary hypoxi...

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Detalles Bibliográficos
Autores principales: Darawshi, Said, Yaseen, Hiba, Gorelik, Yuri, Faor, Caroline, Szalat, Auryan, Abassi, Zaid, Heyman, Samuel N., Khamaisi, Mogher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472507/
https://www.ncbi.nlm.nih.gov/pubmed/32787602
http://dx.doi.org/10.1080/0886022X.2020.1801466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472507/
https://www.ncbi.nlm.nih.gov/pubmed/32787602
http://dx.doi.org/10.1080/0886022X.2020.1801466

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