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Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants
BACKGROUND: Frontotemporal dementia (FTD) is the second leading cause of early onset dementia following Alzheimer’s disease. It involves atrophy of the frontal and temporal regions of the brain affecting language, memory, and behavior. Transactive response DNA-binding protein 43 (TDP-43) pathology i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472585/ https://www.ncbi.nlm.nih.gov/pubmed/32887544 http://dx.doi.org/10.1186/s12868-020-00586-0 |