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Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants

BACKGROUND: Frontotemporal dementia (FTD) is the second leading cause of early onset dementia following Alzheimer’s disease. It involves atrophy of the frontal and temporal regions of the brain affecting language, memory, and behavior. Transactive response DNA-binding protein 43 (TDP-43) pathology i...

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Detalles Bibliográficos
Autores principales:	Venkataraman, Lalitha, He, Ping, Khan, Galam, Harris, Brent T., Sierks, Michael R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472585/ https://www.ncbi.nlm.nih.gov/pubmed/32887544 http://dx.doi.org/10.1186/s12868-020-00586-0

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