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The Structure and Function of DNA G-Quadruplexes

Guanine-rich DNA sequences can fold into four-stranded, noncanonical secondary structures called G-quadruplexes (G4s). G4s were initially considered a structural curiosity, but recent evidence suggests their involvement in key genome functions such as transcription, replication, genome stability, an...

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Detalles Bibliográficos
Autores principales: Spiegel, Jochen, Adhikari, Santosh, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472594/
https://www.ncbi.nlm.nih.gov/pubmed/32923997
http://dx.doi.org/10.1016/j.trechm.2019.07.002